Phenolic compounds versus SARS-CoV-2: An update on the main findings against COVID-19

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dc.contributor.authorTirado Kulieva, Vicente Amirpasha
dc.contributor.authorHernández Martínez, Ernesto
dc.contributor.authorChoque Rivera, Tania Jakeline
dc.date.accessioned2026-03-04T17:10:29Z
dc.date.available2026-03-04T17:10:29Z
dc.date.issued2022-09-19
dc.description.abstractPhenolic compounds are essential due to their antioxidant activity and high antiviral potential. In this context, this review reports the main findings on the effect of phenolic compounds (PCs) against SARS-CoV-2 virus. First, the proven activity of PCs against different human viruses is briefly detailed, which serves as a starting point to study their anti-COVID-19 potential. SARS-CoV-2 targets (its proteins) are defined. Findings from in silico, in vitro and in vivo studies of a wide variety of phenolic compounds are shown, emphasizing their mechanism of action, which is fundamental for drug design. Furthermore, clinical trials have demonstrated the effectiveness of PCs in the prevention and as a possible therapeutic management against COVID-19.en
dc.identifier.citationTirado-Kulieva, V.A., Hernández-Martínez, E., & Choque-Rivera, T.J. (2022). Phenolic compounds versus SARS-CoV-2: An update on the main findings against COVID-19. Heliyon, 8(9), e10702. https://doi.org/10.1016/j.heliyon.2022.e10702
dc.identifier.doi10.1016/J.HELIYON.2022.E10702
dc.identifier.urihttps://hdl.handle.net/20.500.14845/439
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofHeliyon
dc.rightshttps://purl.org/coar/access_right/c_abf2
dc.rights.urihttps://creativecommons.org/licenses/by/4.0
dc.subjectPolyphenols
dc.subjectSARS-CoV-2
dc.subjectCOVID-19
dc.subjectCoronavirus
dc.subjectMedicine natural
dc.subjectImmune system
dc.titlePhenolic compounds versus SARS-CoV-2: An update on the main findings against COVID-19
dc.typehttps://purl.org/coar/resource_type/c_dcae04bc

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